tag:blogger.com,1999:blog-60944759140632890842024-03-13T18:38:09.163-07:00Cookbook, Nutrition and Recipes Cancer Patients - Cooking With CancerIn 2003, tired of seeing the same full cans of supplements on daily rounds and untouched meal trays, Dr. Luis F. Pineda enrolled in Culinard Institute to combine the art of cooking with the knowledge of medicine. His motivation is the patients past and present he has provided care for through his 26 plus years as an oncologist.Cooking With Cancer, Inc.http://www.blogger.com/profile/17490057388112564398noreply@blogger.comBlogger5125tag:blogger.com,1999:blog-6094475914063289084.post-29857707702495941442011-06-06T14:03:00.000-07:002011-06-06T14:04:30.559-07:00Cooking With Cancer Pineda Red WinePositive and negative moments in life are always shared with good friends. As many of you know, one of my passions in life is to increase the quality of life for cancer patients through my knowledge of medicine combined with my training in the culinary arts. <br /><br />Cooking with Cancer, INC. is a non profit, 501 (c) (3), charitable organization designed to dedicate its resources and energy to the research, development, education, and training of these aspects. During the past year, CWC had the pleasure of providing over 1,500 domestic and international oncology patients with free cookbooks and DVD’s. These educational resources enforce healthy living, address certain side effects a patient may experience during chemotherapy or radiation, and promote overall nutrition. <br /><br />Healthy Living, Healthy Lives….Living for a Better Tomorrow is a free educational seminar CWC’s been fortunate to present to corporate business, healthcare providers, hospitals, societies, retirement communities, organizations, cancer centers and private practice providers. Prevention, through education, I feel is the most powerful tool in our fight against cancer.<br /><br />Today, I share with you the latest CWC venture, PINEDA red wine. The wine’s name is homage to my parents. In Spanish, Pineda means rich pine forest and the making of a good wine starts with a rich earth. CWC and International Wines entered into a partnership to create PINEDA and in a few weeks, PINEDA will be distributed throughout Alabama and Mississippi. Local venues close to you such as Whole Foods, Western in Mt. Brook, and Vintage Wines will feature our wine. Our vision is to have this wine promote health, happiness, and compliment good food while supporting a good cause. 100% of the profits from PINEDA will go back into CWC. These funds will help the continuation of free educational resources to oncology patients.<br /><br />Many of you have already joined me in this cause and I am sincerely thankful. As a colleague and personal friend I want to share this with you.<div class="blogger-post-footer">www.cookingwithcancer.org</div>Cooking With Cancer, Inc.http://www.blogger.com/profile/17490057388112564398noreply@blogger.com5tag:blogger.com,1999:blog-6094475914063289084.post-32803443048946096582011-05-27T11:26:00.000-07:002011-05-27T11:28:02.407-07:00Pineda Sonoma County 2008 RED WINE Just Releasedhttp://www.cookingwithcancer.org/wine.html<br /><br />CWC Pineda Wine<br /><br />Pineda Sonoma County 2008 RED<br /><br />What type of wine is Pineda?<br /><br />In Spain, PINEDA means pine forest. As the symbol of Cooking with Cancer the pine tree represents strength, serinity, and a stable, calming presence. Cooking with Cancer is a non-profit organization, begun by oncologist Dr. Luis F. Pineda, with the mission of "helping those affected with cancer to enjoy a better quality of life through good food."<br /><br />CELLARED AND BOTTLED BY PINEDA & THE WINE LIBERATION SOCIETY<br />HEADLDSBURG, CALIFORNIA<br /><br />CONTAINS SULFITES : 750ML : ALCOHOL 14.2% BY VOLUME<br /><br /> <br /><br />Do all proceeds go to non-profit?<br /><br />Yes.<br /><br /> <br /><br />Is red wine good for you ?<br /><br />Yes. Red wine, in moderation, has long been thought of as heart healthy. The alcohol and certain substances in red wine called antioxidants may help prevent heart disease by increasing levels of "good" cholesterol and protecting against artery damage.<br /><br /><br />Where is Pineda Sonoma County 2008 located?<br /><br />It can be found at:<br /><br />Wholefoods on Hwy 280<div class="blogger-post-footer">www.cookingwithcancer.org</div>Cooking With Cancer, Inc.http://www.blogger.com/profile/17490057388112564398noreply@blogger.com1tag:blogger.com,1999:blog-6094475914063289084.post-69787102102966561942010-11-22T08:34:00.000-08:002010-11-22T08:41:04.996-08:00B-metro MagazineCheck out our full article from the B-Metro Magazine about Cooking With Cancer.<br /><br />http://www.cookingwithcancer.org/pdfs/bmetro.pdf<div class="blogger-post-footer">www.cookingwithcancer.org</div>Cooking With Cancer, Inc.http://www.blogger.com/profile/17490057388112564398noreply@blogger.com3tag:blogger.com,1999:blog-6094475914063289084.post-81008697982550463172010-05-24T08:45:00.001-07:002010-05-24T08:55:01.662-07:00Taste and Smell in Cancer | Nutrition for Cancer Patients | Cooking With Cancer<span style="font-weight:bold;">The Cooking with Cancer Concept:</span><br /><span style="font-weight:bold;">Taste and Smell in Cancer </span><br />WARNING<br />The following content is intended<br />as a scientific explanation of the<br />breakdown in taste and smell.<br />Material contains facial photography<br />of sensitive, even described by<br />some as graphic, illustration<br />seen in chemotherapy and radiation<br />therapy patients.<br />Viewer discretion is advised.<br />Luis F. Pineda, M.D., M.S.H.A.<br /><br /><span style="font-weight:bold;">Taste and Smell in Cancer:</span><br /><br />Introduction<br /><br />With the aging process and prolongation of life, cancer is, and will<br />continue to be, a major health issue. One of many, not the least important, yet critical problems, is the ability of patients with cancer to support normal nutrition. <br /><br />Basic assumptions are that cancer, a state of abnormal cellular behavior, imposes a catabolic state on the individual.<br /><br />Documented further by recent technological development of the PET scan, we are able to obtain images of cancer cell locations on the basis of the incorporation of radioactively labeled glucose as the result of their hyperactive metabolism. If the individual is unable to keep up to the demand on the basis of incorporation or intake of nutrients, then malnutrition and weight loss ensues. There is a possible participation of endogenously released cytokines such as Interleukins or a tumor necrosis factor.<br /><br />Additionally, the cancer treatment modalities of today are causes of substantial changes to taste, smell, and appetite by either psychological trauma, neurochemical changes or inflammatory cytolytic damage to the mouth, nose, or gastrointestinal tract. Things are further worsened by cancer therapy complications, including infection, nausea, and vomiting.<br /><br />Palliative modalities of pain control, use of narcotic pain medications such as codeine, morphine and analogs, which directly affect the central nervous system (limbic system), affect the function of the gastrointestinal tract causing severe constipation, nausea and vomiting. Most culinary literature available addresses these issues by attempting to minimize the smell of preparation, the temperature, and color. By this, I mean, historically it was recommended to consume white, cold, and non smelly foods versus hot, red, and smelly foods. By garnishing and coloring the food we can now impact the taste and intake and create appeal.<br /><br />Most nutritional literature available addresses these issues by the<br />drastic use of involuntary nutrition such as total parenteral nutrition or<br />TPN, tube feeding via gastrointestinal infusion through nasogastric or<br />percutaneous endoscopicly placed gastric tube (PEG). All of these are<br />unappealing and excessively expensive interventions. The use of high<br />calorie oral supplements such as puddings, bars, and boosters have<br />failed despite their easy availability. This failure is due to patient<br />intolerance, mostly because of the high carbohydrate content, which<br />makes the products excessively sweet.<br /><br />Appetite stimulants such as Marinol® (tetrahydrocannabinol) or Megace® (megastrol) have the disadvantage of causing mental status changes and sedation. They are exceedingly expensive, or in the case of Megace, there is an inability to use it in cases of hormone dependent cancers (ex. prostate cancer - a very common cancer in adult males). There is also the potential for abnormal blood clotting which is already heightened in cancer.<br /><br />The management of cancer induced taste alteration should be aimed at maintaining optimal nutrition (Brodie 1998), but above all, quality of life.<br /><br />Taste<br /><br />Flavor is a complex mixture of sensory inputs (Smith 2001). Its<br />components are gustation (taste), olfaction (smell, perhaps more<br />important than credited), and tactile (mechanics of chewing).<br />Traditionally described qualities of taste are sourness, sweetness,<br />bitterness, and saltiness. Some others may exist, notably Umami,<br />(Japanese translation “delicious”). This is most elicited by glutamate,<br />an enhancer of taste commercially available as monosodium<br />glutamate or MSG. In 1908, Ikeda from Japan, recognized it as the<br />tasting chemical component of the brown algae soup Kombu.<br />This Umami concept was developed by Chaudhari and Roper from<br />the University of Miami in 1998. Loosely implying a “meaty” taste, this<br />concept is still not widely accepted.<br /><br />Most recent research has documented Umami receptors mediated via mGluR4 glutamate receptor, as well as mT2R8 denatonium receptors located in the mouth, glutamate related and cyclic AMP conducted via calcium channels. Sodium glutamate is a food enhancer that is very similar in taste to common cooking salt and definitely enhances the pleasantness of food by at least 50% or better at appropriate culinary levels (Yamaguchi, 1984). The main concern has been the flatulence and abdominal discomfort sometimes associated with it. It is blamed for obesity in oriental people and occasionally allergic reactions. Nonetheless, the significantly lesser amount of Sodium content when compared with regular cooking salt (65% less) has a potentially significant<br />impact in hypertension management and can be a great benefit.<br /><br />For years it was believed the tongue was the source of taste receptors, all selectively located by geography and specificity (i.e. sweetness located at the tip or sourness to the side).<br /><br />The fact is that all the mouth, not only the tongue, possesses<br />72 receptors that are capable of responding to different stimuli regardless<br />of the quality and nature. An example is the following salt receptor<br />diagram. It highlights the importance of the electrolyte channels and<br />the electrical nature of the transmission.<br /><br />Recent studies have described more specific receptors for tasting<br />sensations and further research continues.<br /><br />Taste buds, receptors and conductors will respond to a sensation<br />in particular, but to all sensations to a certain degree. So, the receptor<br />for sweet will respond to mostly sweet taste, but to bitter, sour, and salty to a lesser degree (Wickham 1999). The locations of the receptors are the tongue, soft palate, glossopalatine arch, and the posterior portion of the pharynx. Most taste receptors are located on the tongue. They are located within the papillae projection giving the tongue its velvety appearance. Several geographical areas on the tongue are identified. As shown, the tip is rich in mushroom like taste buds. The taste buds on the back of the tongue are flat circumvallates distributed in an inverted V. The taste buds on the lateral portion of the tongue are foliates. The filiform lack tasting receptors, yet provide tactile sensations. The concept of the geographic tongue (sweet, hot, salty) is no longer sustainable as each receptor is capable of reacting to more than one kind of stimuli 73<br />at a time. They are not unique to a given taste, nor are they<br />geographically distributed as previously thought.<br /><br />The taste buds contain about 50 to 100 taste cells. They are<br />arranged in an onion shaped fashion with small microvilli poking<br />through the opening at the top (taste pore).<br />The vehicle for taste is the saliva (Schiffman 1994). Tastants, or<br />food chemicals dissolved in saliva, contact the receptors via the pore,<br />activating the chemical G-protein (gustducin and transducin)<br />receptors (ion channels) that transform into electrical impulses that<br />are then sent to the brain.<br /><br />The process of depolarization activates the receptors. The inside<br />and outside of the cells are in constant electrical balance. In the case<br />of taste receptors, they are negatively charged inside. The contact<br />with the stimulating agent tends to neutralize or turn the inside<br />positive. This creates a cascade of electrical current, which gets<br />passed through the nerve line, the end of which releases a chemical<br />neurotransmitter to communicate in relay to the next nerve cell until<br />it arrives at its destination in the brain.<br /><br />As the receptor, nerve line, relay points, and end stations are<br />electrically activated they become unable to respond to another stimuli<br />(taste) until delivery, and then become depolarized again. This is called<br />the refractile or recovery phase. The impulses from the taste are then<br />transmitted to the cerebrum via cranial nerves V, VII, IX, and X<br />(Bender 1999).<br /><br />Chorda tympani (CT) are the primary innervation pathway for the<br />anterior tongue receptors in addition to providing the taste receptors<br />structural and functional fitness (McCluskey 2002). Surgical<br />alteration of the tongue leads to loss of sweet and salty receptors.<br />Surgery of the palate can alter sour and bitter receptors (Grant 2000).<br />The final receptor, thought to be the parietal operculum near the<br />Rolando’s fissure, is now believed to be mostly located in the insula<br />(This 2005).<br /><br />The likelihood is that there is not a single taste center in the<br />brain, but it is likely the electrical interaction of many areas allowing<br />the brain to construct a global sensation.<br /><br />Smell<br /><br />Smell has played a very special role in the natural evolution of<br />animals, especially the mammals. Many of them are nocturnal and<br />they had to depend on olfactory guidance to detect food, avoid<br />predators, recognize territories, social groups, and even sexual contact<br />(McGee 1984).<br /><br />The human olfactory area is approximately 16 square centimeters<br />as compared with almost 150 square centimeters in dogs.<br />S mell and taste cannot be separated. “Smell and taste form a<br />single sense, of which the mouth is the laboratory and the nose is the<br />chimney. To be more specific, of which, one serves for the tasting of<br />actual bodies and the other for the savoring of their gases”<br />(Brillat-Savarin 1994).<br /><br />Little has been known about smell until recent years.<br />Researchers have earned two major Noble prizes in physiology<br />and medicine (Linda Buck and Richard Axel 2004) by defining<br />the olfactory receptor protein as shown.<br /><br />This system still depends on receptor activation, transmission of<br />electrical impulses via cyclic AMP (amino mono phosphate), and<br />electric exchange interaction with sodium exchange.<br /><br />Often misunderstood, the act of smelling does not happen<br />exclusively by inhaling aromas via the nose, but rather by a<br />pheromontal action. This mixture of combined saliva, product, and<br />evaporation penetrates the back of the nose via the back soft palate<br />and activates the smell receptors.<br /><br />The human sense of smell depends on the functioning of cranial<br />nerve I or the olfactory nerve, for qualitative odor sensations such as<br />the smell of roses, lemon or grass and the ophthalmic and maxillary<br />portions of cranial nerve V the trigeminal nerve for somatic sensory<br />overtones of odorants such as warmth, coolness, sharpness, and<br />irritation.<br /><br />The olfactory neuroepithelium is located over the cribiform plate,<br />the superior septum and a segment of the superior turbinate and is<br />rich in smell receptors.<br /><br />A s in the case of taste, odors attach to and dissolve within the<br />covering mucus layer to obtain contact with the receptors (Doty R.L.<br />Bromley, S.M. 1997). Taste, smell, and other impulses will make<br />their way via nerve conduction to the brain where the ultimate<br />arrangement of impulses gets coded for the final perception.<br /><br />Thermal and Mechanical Receptors<br /><br />Other minor receptors include:<br /><br />• Mechanical: tactile sensing of texture (crunchy, soft, hard,<br />dry, wet)<br />• Thermal: temperature sensation<br /><br />All of this is aided by mastication, the mechanical dismembering<br />of the food bolus into smaller particles capable of being mixed with<br />saliva, and the carrying of particles to contact the taste receptors via<br />fluid or smell receptors via gases (pheromontal). The process of<br />mastication reduces the size of the particles to be swallowed and<br />mixes the saliva to bind all together in a safe bolus. This mixes the<br />food for better exposure to digestive enzymes.<br /><br />Most people will chew about twenty times before swallowing;<br />however, under normal circumstances the more likable the food the<br />longer the mastication as a source of pleasure. The slower and longer<br />the mastication, the more opportunity for odorants, which are<br />volatile molecules, to travel up to the smell receptors via the back of<br />the mouth. This is relevant for the chewing gum industry.<br /><br />Enhancers<br /><br />Peppers are used in many cultures as a flavor enhancer. Capsaicin,<br />the active substance in peppers, increases the blood flow to<br />the mouth and activates VRI receptors, a membrane channel protein,<br />which exchanges calcium in and out of the cells. Capsaicin has four<br />different subunits, which located in different sites of the mouth,<br />count for the different effect in flavor by different kinds of peppers.<br />Being fat soluble and heat sensitive improves the taste for fatty foods.<br />Peppers are, if nothing else, taste enhancers. Their physiological<br />function is based on three principles.<br /><br />• An overwhelming inducer of blood supply to the mouth (please<br />note to yourself what happens when exposed to a minimal amount of<br />peppers on your lips) that causes an increased production of saliva,<br />a vehicle to the distribution of elements of flavor in the mouth, and<br />rapid heart rate with an increase in bronchial secretions and indices<br />perspiration (cooling effect).<br />• They are depolarizers of the electrical charges to the taste and smell<br />receptors.<br />• They are a direct stimulant of the brain via pain sensory pathways.<br />This is done by reducing the availability of substance P and<br />increasing levels of prostaglandins, both crucial elements of the<br />inflammatory human response.<br /><br />All these enhance the brain capacityy for taste and smell. This<br />makes the act of eating more pleasurable.<br /><br />Well known to other cultures, such as Latin America (jalapeno,<br />ancho), India (sanaam, dundicut), and China (tien tsin pepper), the<br />use of chilli peppers is intrinsically part of the culture.<br /><br />Chilli peppers, originally from Latin America, were used by Maya,<br />Inca and Aztecs. Chilli peppers were taken to the old world by<br />Christopher Columbus as a substitute to the better-known peppers.<br />The medicinal effects were recognized early on by pre-Columbian<br />Mayan. They prepared chillatolli, maize flour mixed with chilli, for all<br />kinds of respiratory ailments. The Aztec would use the direct fruit<br />for toothache pain control. Tukano Indians in Colombia used it for the<br />treatment of hangovers and Mayans and Aztecs as infection control for<br />open wounds.<br /><br />The assumption that peppers are an anti-cancer chemical is less<br />important. They are otherwise well recognized as a pain controller and<br />widely used in the United States of America as a localized anti-arthritis<br />medicine. Peppers are not just “hot” they are used as flavor<br />enhancers, for example Paprika.<br /><br />They are all graded in the intensity of the heat according to the<br />Scoville Heat Unit System (Wilbur L. Scoville 1912). This scale is<br />human rated so consequently, this is subjective and liable to human<br />error. The scale establishes pungency by dilution and testing. In<br />essence, they attempt to document the number of dilution times in a<br />neutral liquid where a normal human being can no longer detect the<br />bite. The most scientific measurement is a high performance liquid<br />chromatography which extracts and measures capsaicinoid chemicals.<br /><br />SCOVILLE HEAT UNITS SCALE<br /><br />The following is a list of chiles, put into a scale to show the relative<br />pungency levels and their Scoville Heat Units.*<br /><br />Name Pod Type Species Scoville Units<br />Orange Habanero Habanero C. chinense 210,000<br />Red Habanero Habanero C. chinense 150,000<br />Tabasco Tabasco C. frutescens 120,000<br />Tepin Tepin C annuum 75,000<br />Chiltepin Tepin C. annuum 70,000<br />Thai Hot A sain C. annuum 60,000<br />Jalapeno M Jalapeno C. annuum 25,000<br />Long Slim Cayenne Cayenne C. annuum 23,000<br />Mitla Jalapeno C annuum 22,000<br />Santa Fe Grande Hungarian C. annuum 21,000<br />Aji Escabeche A ji C. baccatum 17,000<br />Long Thick<br />Cayenne Cayenne C. annuum 8,500<br />Cayenne Cayenne C. annuum 8,000<br />Pasilla Pasilla C. annuum 5,500<br />Primavera Jalapeno C. annuum 5,000<br />Sandia N ew Mexican C. annuum 5,000<br />NuMex Joe E. Parker N ew Mexican C. annuum 4,500<br />Serrano S errano C. annuum 4,000<br />Mulato A ncho C. annuum 1,000<br />Bell Bell C. annuum 0<br /><br />Capsaicin<br /><br />Chemical Structure of Capsaicin<br />Capsaicin is the most widely recognized chemically active<br />ingredient in chilli peppers. Contrary to popular belief, the heat is<br />not located in the seeds, but in the placenta, which are little sacs<br />located in the inner wall of the fruit. When opening the fruit they tend<br />to splash into the seeds since they are very fragile and easy to rupture.<br />Capsaicin binds directly to the receptors in tasting but can be unbound<br />by casein, a protein obtained from milk, beans, nuts, and chocolate<br />that is used as a moderator of pungency.<br /><br />To date, there are fourteen different capsaicins named<br />capsaicinoids. Each one has a quite unique and characteristic property<br />on the nature of the bite, the location in the mouth that gets activated,<br />and the duration of its action.<br /><br />• Nordyhydrocapsaicin gives a mellow warming effect, rapidly on<br />and off, mostly at the front of the mouth and the palate.<br />• By comparison, dihydrocapsaicin is more potent and affects the<br />middle of the mouth and palate.<br />• Homohydrocapsaicin is a harsh, sharp irritant, with a slow onset<br />but a longer duration at the throat and back of the tongue.<br />L ikewise, heating of the tip of the tongue produces a sweet taste,<br />while cooling elicits a sour sensation.<br /><br />Taste and Smell Behavior<br /><br />Most flavor preferences and aversions are learned. There is an<br />innate liking to sweetness perhaps associated with common eating<br />of fruits, and a disliking to bitterness that is mostly associated with<br />poisonous and bitter alkaloids. Social customs, opportunities, and<br />private associations with pleasant and painful moments are imprinted<br />from early childhood. This has been experimentally exemplified in<br />well-known studies such as the case of Pavlov and his experiences with<br />dogs. There are repeated reports of food “cravings” rich in needed<br />fundamental electrolytes or nutritional items. For example, water and<br />salt in dehydration, water and carbohydrates in cases of Diabetes<br />Mellitus, and pregnancy cravings.<br /><br />Preabsorptive Satiety refers to the point in time when a sense of<br />fulfillment of eating arises. Several mechanisms are believed 82<br />associated with this since the actual biochemical satisfactions of need<br />cannot be corroborated, so pressure receptors in the wall of the<br />stomach, chemical receptors in the wall of the intestine, or<br />downgraded affinity of the tasting receptors via blood glucose has<br />been sited (this could be nonetheless overridden by cultural pressures,<br />for example obesity in the USA). It is unclear why someone becomes<br />full after a meal or why a given desired food intake becomes sickening<br />when taken in excess.<br /><br />Pathophysiology<br /><br />The life span of a taste cell is approximately ten days. Because<br />of this rapid proliferation, they become highly susceptible to cellular<br />destruction during chemotherapy (Strohl 1984). In cancer patients in<br />general, there is a higher taste threshold as a result of a decrease in<br />the number of taste buds (Stubbs 1989).<br /><br />Cytokines are proteins manufactured by the body. They influence<br />the cellular behavior by inducing specific cellular functions. Cancer<br />drives up the production of them (Interleukins, tumor necrosis factor).<br />They are known for lowering the threshold for bitter sensations<br />(Davidson 1998).<br /><br />Radiation therapy to the head and neck area is known to cause<br />alteration of taste: initially at 20Gy (the unit of measurement in<br />radiation) you experience alteration of taste. This increases 50% at 30Gy and Becomes permanent at 60Gy (Madeya 1996). Radiation directly reduces the number of taste buds and damages the 83 microvilli of the cells. Initially this impairs the bitter and salty sensations and later to a lesser degree the sweet taste (Mossman K.<br />1978).<br /><br />Chemotherapy, on the other hand, lowers the threshold for bitter<br />tastes and increases it for the sweet tastes (Madeya 1996). Many<br />patients complain about a metallic taste. The main offending agents<br />are Nitrogen Mustard, Cisplatin, Cyclophosphamide, and Doxorubicin.<br />Repeated adverse reaction to chemotherapy has been known to<br />develop into a behaviorally adverse reaction by the patient according<br />to Pavlov’s mechanism (Bender 1999).<br /><br />Damage by chemotherapy:<br />Mucositis<br />Damage by Infections:<br />Herpes Zoster Infection<br />Damage by Radiation Therapy:<br />Osteonecrosis<br /><br />Does it make any difference?<br /><br />Beyond the issue of pure quality of life and the enjoyment of<br />eating, would nutrition make any difference? For most anyone,<br />including medical or neophytes, the answer is yes. Usually, this<br />question is not primarily addressed and sometimes priority is the<br />second or third tier in nutritional importance.<br /><br />Food for thought:<br />• The fundamentals are misunderstood in importance.<br />• The Positron Emitting Tomography (PET scan), the up-to-date<br />technological tool in oncology, precisely depends on the cellular<br />utilization of glucose by cancer cells.<br /><br />• In 1998 a double blind, random study with a small sample,<br />showed that administration of zinc sulfate three to four times per<br />day restored not only the acuity of taste but also slowed the<br />worsening of taste alterations and taste bud anatomy (Ripamonti<br />1998).<br /><br />• Monosodium Glutamate, commonly used in oriental food, is<br />becoming a good candidate as a “flavor enhancer”, not only<br />because of its salty taste but it stimulates Umami, the latest<br />recognized taste, triggering release of glucagons and insulin<br />(This 2005). <br /><br />Alcohol and Health<br /><br />The relationship between alcohol and health has been long-lived<br />and controversial. For years medical schools have taught students the<br />serious adverse effects including alcoholism and its social<br />consequences, as well as the more physical impacts including liver<br />cirrhosis and fetal alcohol syndrome.<br /><br />For moderate drinkers, indications show a mortality rate 16%<br />lower than the 28% seen in non-drinkers (Boffetta, Fuchs). The<br />National Institute on Alcohol Abuse and Alcoholism has established<br />the greatest longevity with the consumption of one to two drinks per<br />day (Ellison 1993). A drink is defined as a five-ounce glass of wine,<br />one ounce of hard alcohol or one can of beer.<br /><br />The most protective effect is on the cardiovascular and circulatory<br />systems by increasing levels of HDL (high density lipoprotein) or the<br />good cholesterol, decreasing thrombosis, reducing fibrinogen,<br />increasing fibrinolysis and reducing arterial spasm during stress<br />(Paassilta 1998).<br /><br />Moderate alcohol consumers suffer a lesser number of heart<br />attacks and arteriosclerosis. They have a lower risk for dementias<br />including Alzheimer’s disease (Mukamal 2003), and there is a lower<br />incidence for metabolic syndrome (Matthew 2004). They all seem<br />associated with the presence of resveratrol, a phytoalexin<br />chemical found in the skin of the red grapes used in the production<br />of red wines.<br /><br />For our purposes, alcohol seems to have an enhancing property to<br />appetite and taste, interestingly enough, by enhancing the sense of<br />smell.<br /><br />Food Chemistry<br /><br />What healthy people like:<br />• Taste of fat (concept of marveling)<br />• Taste of sugar (concept of caramelizing)<br />Recommendations:<br />• Because of the described metallic taste, use plastic utensils<br />(Stubbs 1989).<br />• Patients should eat small and frequent meals throughout<br />the day (Sherry 2002).<br />• Chilled or frozen foods are more acceptable than warm food<br />(Brodie 1998).<br />• Mouth care is of crucial importance (Sherry 2002).<br />• Provide rapid shifting tastes:<br />1. By enhancing receptors activities (chilli pepper).<br />2. By cleansing of receptors<br />a. (ginger/pickles)<br />3. By use of sauces of the nature of coulis<br />(fruit based sauce with no fat)<br />• Portions should be small.<br />• Presentation should be simple and colorful.<br />• Drink a glass of red wine before a meal. (Alcoholic beverages<br />are used as an appetite stimulant.)<br /><br />Disclaimer<br /><br />This paper is not intended to be a scientific presentation in as<br />much as a compilation of information and ideas in the attempt to<br />improve quality and perhaps quantity of the lives of patients afflicted<br />by cancer.<br /><br />The hope is to provide a simple, superlative, and better quality of<br />life to patients afflicted with cancer.<br /><br />Personal Statement<br /><br />My quest in taste and smell in patients afflicted with cancer has been<br />accomplished with the help of God and those patients for whom this<br />manuscript is dedicated and intended.<br /><br />Bibliography<br />Ackerman, B., & Kasbekar, N., (1997). “Disturbances of taste and smell induced<br />by drugs.” Pharmacotherapy 17: 482-496.=<br />Bender, C. (1999). Taste Alteration. Nursing management of symptoms associated<br />with chemotherapy. J. Yasko, Bala Cynwyd, PA: Meniscus Health Care<br />Communicatios.: 55-63.<br />Brillat-Savarin, J.-A. (1994). The Physiology of Taste. Harmondsworth, Middlesex,<br />England, Penguin Books.<br />Boffetta, P. and Garfinkel,L. 1990. Alcohol drinking and mortality among men<br />enrolled in an American Cancer Society prospective study. Epidemiology Sep,<br />1(5):342-8<br />Brodie, K. (1998). Taste alterations. Clinical guidelines for symptom management<br />in oncology. F. P. R. Cunningham. New York, Clinical insights Press: 73-77.<br />Davidson, H., Pattison, R., & Richardson, R. (1998). “Clinical undernutrition<br />sates and their influence on taste.” Prosceeding of the nutrition Society 57:<br />20-30.<br />Doty R.L. Bromley, S.M., M. P., Hummel, T. (1997). Laterality in human nasal<br />chemoreception. Cerebral assymetries in sensory and perceptual processing. C. S.<br />New York, Elsevier: 497-542.<br />Ellison, R. Does moderate alcohol consumption prolong life? American Council in<br />science and health, New York 1993<br />Fuchs, C.S. et. al.1995. Alcohol consumption and mortality among women. New<br />England Journal of Medicine May 11;332(19(:1245-50<br />Grant, M., & Kravits, K., (2000). “Symptoms and their impact on nutrition.”<br />Seminars in Oncology Nursing 16: 113-121.<br />Madeya, M. (1996). “Oral complications from cancer therapy.” Oncology Nursing<br />Forum 23(part 1): 801-807.<br />Matthew S. et. al. alcohol consumption and the prevalence of the metabolic<br />syndrome in the USA. Diabetes care. 27:2954-2959, 2004<br />McCluskey, L., Hill, D. (2002). Sensitive periods for the effect of dietary sodium<br />restrictiion on intact and denervated taste receptor cells, American Physiological<br />Society. 2004.<br />McGee, H. (1984). On Food and Cooking: The Science and Lore of the Kitchen.<br />New York, SCRIBNER.<br />89<br />Mossman K., Henkin, R. (1978). “Radiation-induced changes in the taste acuity<br />in cancer patients.” International Journal of Radiation Oncology 4: 66-670.<br />Mukamal, K. et al. Prospective study of alcohol consumption and risk of dementia<br />in older adults. JAMA 2003 (march19) 289, 1405-1413<br />Paassilta, M. et al. Social alcohol consumption and low Lp(a) lipoprotein<br />concentrations in middle aged Finnish men: population based study. British<br />Medical Journal 1998 Feb14:316(7131)<br />Ripamonti, C., Zecca, E., Brunelli, C., Fulfaro. F., Villa, S., Balzarini, A., et al.<br />(1998). “A randomized, controlled clinical trial to evaluate the effects of Zinc<br />sulfate on cancer patients with taste alterations caused by head and neck<br />irradiation.” Cancer 82: 1938-1945.<br />Schiffman, S. (1994). “Changes in taste and smell: drug interactions and food<br />preferences.” Nutrition Reviews 52 (8, Pt.2): s11-s14.<br />Sherry, V. W. (2002). Taste Alteration Among Patients With Cancer.<br />Smith, D., Margolskee, R. L. (2001). “Making Sense of Taste.” Scientific<br />American: 32-39.<br />Strohl, R. (1984). “Understanding taste changes.” Oncology Nursing forum<br />85(3): 81-84.<br />Stubbs, L. (1989). “Taste changes in cancer patients.” Nursing Times 83(3):<br />49-50.<br />This Herve` (2005) “Molecular Gastronomy” Columbia University Press.<br />Wickham, R. S., Rehwald, M., Kefer, C., Shott, S., Abbas, K., Glynn-Tucker, E.,<br />et al. (1999). “Taste changes experienced by patients receiving chemotherapy.”<br />Oncology Nursing forum 26: 697-705.<br />Yamaguchi, S. Takahashi, C. (1984)J food sci. 49(1) 82:85 v<br /><br />Bibliography on Pepper:<br /><br />Christopher, John R. Capsicum, Springville, Utah: Powder River Press, 1980.<br />Graham, D., et al. “Spicy Food and the Stomach: Evaluation by Videoendoscopy.”<br />Digestive Disease Section. Veterans Administration Medical Center and the Baylor<br />College of Medicine, Houston. Journal of the American Medical Association.<br />1988; 260:3473-3475.<br />Kawada et al. “Effects of Capsaicin on Lipid Metabolism in Rats Fed High Fat<br />Diet,” American Institute of Nutrition, 1986; 1272-1278.<br />90<br />Lacroix, J.S., et al. “Improvement of Symptoms of Non-Allergic Chronic Rhinitis<br />by Local Treatment with Capsaicin.” Clinic of Otorhinolaryngology, University<br />Cantonal Hospital, Geneva, Switzerland. Clin. Exp. Allergy. September 1991,<br />21(5); 595- 600.<br />Mahindru, S.N. Spices in Indian Life, New Delhi: Sultan Chand & Sons, 1982.<br />Matucci-Cerinic, M., et al. “Effects of Capsaicin on the Metabolism of<br />Rheumatoid Arthritis Synoviocytes in Vitro.” Comment in: Ann. Rheum. Dis.<br />49(8):653, August, 1990. Institute for Clinical Medicine IV, University of<br />Florence, Italy.<br />Mowrey, Daniel B. Proven Herbal Blends. New Canaan, CT: Keats Publishing, Inc,<br />1986.<br />Sicuteri, F., et al. “Substance P Theory: A Unique Focus on the Painful and<br />Painless Phenomena of Cluster Headache,” Headache, Jan. 1990; 30(2):69-79.<br />Takeuchi, K., et al. “Gastric Motility Changes in Capsaicin- induced<br />Cytoprotection in the Rat.” Kyoto Pharmaceutical University, Jpn. J. Pharmacol.<br />1991; 55:147-155.<br />Visudhiphan, S. et al. “The Relationship Between High Fibrinolytic Activity and<br />Daily Capsicum Ingestion in Thais.” Hematology Division. Department of<br />Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 7,<br />Thailand. The American Journal of Clinical Nutrition 35,: June 1982, 1452-1458.<br />Herbal Research Foundation, Boulder, Colo., 1-800-748-2617.<br />Natural Ovens of Manitowoc, 4300 CR Country Rd., P.O. Box 730, Manitowoc,<br />Wis., 54221-0730, (414) 758-2500.<br />This Herve (2005) “Molecular Gastronomy” Columbia University Press.<br />Wickham, R. S. Rehwaldt, M., Kefer, C., Shott, S., Abbas, K., Glynn-Tucker, E.,<br />et al. (1999). “Taste changes experienced by patients receiving chemotherapy.”<br />Oncology Nursing forum 26: 697-705.<br />Yamaguchi, S. Takahashi, C. (1984) J food sci. 49(1) 82: 85 v.<div class="blogger-post-footer">www.cookingwithcancer.org</div>Cooking With Cancer, Inc.http://www.blogger.com/profile/17490057388112564398noreply@blogger.com0tag:blogger.com,1999:blog-6094475914063289084.post-13357259220037210502010-04-28T10:29:00.000-07:002010-04-28T11:49:58.692-07:00Welcome to Cooking With Cancer by Dr. Luis F. Pineda M.D<span class="subtitle"><span style="font-weight: bold;"><span style="font-weight: bold;"></span>"Helping those afflicted with cancer to enjoy a better quality of life through good food."</span><br /> </span><br /> Cooking with Cancer is a program designed specifically for cancer care of those persons who are afflicted with cancer, care givers of the patients, and all of those who work in the healthcare industry. The content is recipes researched and tested on patients undergoing chemotherapy and radiation.<br /><br />Our goal is to provide a greater understanding of the breakdown in taste, smell and digestion so recommendations for patients are most effective.<br /><br />In 2003, tired of seeing the same full cans of supplements on daily rounds and untouched meal trays, Dr. Luis F. Pineda enrolled in Culinard Institute to combine the art of cooking with the knowledge of medicine. His motivation is the patients past and present he has provided care for through his 26 plus years as an oncologist.<br /><br /> <p> <!-- PARAGRAPH 1 --> <!-- PARAGRAPH 2 --> <span class="subtitle">Some of our goals in the area of taste and smell include:</span></p> <p>Developing taste and smell laboratory dedicated to patients suffering with cancer.</p> <p>Fund clinical research dedicated to establish the causes, nature and treatment of the changes which cancer treatment introduces to the break down of patients taste and smell.</p> <p>Developing of recipes with Institutions of Education in Nutrition and incorporating cooking during training sessions.</p> <p>Developing scholarship aimed to favor career changes oriented to the catering of patients with cancer and their needs.</p> <p>Developing curriculum changes, in colleges and universities, to recognize and study taste and smell changes of patients suffering of cancer and treatments.</p> <p>Our company's utilization of profits:</p> <ul><li>Never to be utilize for financial gain of the officers. </li><li>Always reinvest into the corporation. </li><li>Developing of new programs. </li><li>Payment of expenses. </li><li>Printing of literature. </li><li>Developing scholarship in Nutritional Education for cancer cooking, recipe and research development. </li><li>Direct assistance for patients in financial or nutritional needs.</li></ul>Keep checking back for recipes, research and other talk related to oncology and cooking.<br /><br /><a href="http://www.cookingwithcancer.org">Nutrition and Recipes for Cancer Patients - Cooking With Cancer</a><br /><br />Thanks for reading,<br /><br />Luis Pineda<br />www.cookingwithcancer.org<div class="blogger-post-footer">www.cookingwithcancer.org</div>Cooking With Cancer, Inc.http://www.blogger.com/profile/17490057388112564398noreply@blogger.com2